With the support of




Under the aegis of


Provincia Ravenna


Comune Ravenna


Scientific Sessions

Print Full Programme
Print Day 1

Thursday, 8 September


Registration and posters set-up


Welcome and Opening of the congress


Molecular Oncology

Chairs: Stefano Piccolo (Padua)
Rosa Bernardi (Milan)

Stefano Piccolo (Padua)

TGFβ signaling and metastasis

Pier Giuseppe Pelicci (Milan)

Regulation of self renewal in cancer stem cells

Ruggero De Maria (Rome)

Targeting cancer stem cells in solid tumors


ABCD Lecture

Liz Williams (New York, NY, USA)

What's in a picture? The temptation of image manipulation


Coffee break


AIRC Lecture

Tom Misteli (Bethesda, MD, USA)

Genome cell biology


Special presentation

Alberto Luini (Naples)

Euro-BioImaging, a diffuse European infrastructure for advanced light microscopy: the Italian side


Poster session A and buffet dinner

Print Day 2

Friday, 9 September


Novel Mechanisms of Cell Communication and Perspectives for Therapies

Chairs: Maria Pia Cosma (Barcelona, Spain)
Stefano Pluchino (Cambridge, UK)

Maria Pia Cosma (Barcelona, Spain)

Dissecting functions of Wnt signalling in cell reprogramming

Stefano Pluchino (Cambridge, UK)

Secreted signalling vesicles and neural stem cell functional plasticity

Manuel Álvarez Dolado (Sevilla, Spain)

Cell fusion as a regenerative mechanism


SIBBM Lecture

Maria Leptin (Heidelberg, Germany)

The genetic determination of complex cell shapes


Coffee break


Cell Biology of Disease

Chairs: Alessandra Boletta (Milan)
Marco Sardiello (Houston, TX, USA)

Alessandra Boletta (Milan)

The role of the polycystins in promoting and maintaing renal tubular structure to prevent cystogenesis

Marco Sardiello (Houston, TX, USA)

Lysosomal enhancement as a therapeutic strategy for neuronal ceroid lipofuscinoses

Antonella De Matteis (Naples)

Cell biology and pharmacology of proximal tubular dysfunction in Lowe syndrome


Free time


Neural Development

Chairs: Francesca Peri (Heidelberg, Germany)
Carla Margulies (Munich, Germany)

Francesca Peri (Heidelberg, Germany)

Microglia: the guardians of the developing brain

Carla Margulies (Munich, Germany)

Chromatin and Behavioral Plasticity: Toward an understanding of the role of chromatin in long-term memory formation

Paolo Macchi (Trento)

Send the message: mechanisms and biological significance of mRNA localization in the nervous system


Coffee break


Main Lecture

Tom Kirchhausen (Boston, MA, USA)

Dynamics of endocytosis


Special presentation

Ruggero Pardi (Milan)

Promoting High Standards of Graduate Education in Biomedicine and Biotechnology in Italy: the NEIDOS Web Portal


Poster session B and buffet dinner

Print Day 3

Saturday, 10 September


Systems Biology

Chairs: Diego di Bernardo (Naples)
Andrea Ciliberto (Milan)

Diego di Bernardo (Naples)

Systems Biology approaches to understand gene function and drug mode of action

Andrea Ciliberto (Milan)

Why it is so difficult to make a model of the Spindle Assembly Checkpoint

Neil Lawrence (Sheffield, UK)

Between systems and data-driven modeling for computational biology: target identification with Gaussian processes


Coffee break


FIEO Lecture

Christer Betsholtz (Stockholm, Sweden)

Cell-cell signaling in the regulation of angiogenesis and vascular permeability


Free time


Special Interest Groups • Parallel Sessions

  1. Mechanisms of Signal Transduction
  2. Stem Cells, Development and Regenerative Medicine
  3. Membrane Trafficking and Organelle Biogenesis
  4. Cell Stress: Survival and Apoptosis

Mechanisms of Signal Transduction

Chairs: Annarosa Arcangeli (Florence)
Sara Sigismund (Milan)


Emilio Hirsch (Turin)

Genetic modeling of PI3K inhibition


Veronica Astro (Milan)

Exploring liprin-α1-mediated cell migration and invasion

Lidia Avalle (Turin)

STAT3 enhances migration and invasion in mammary tumor cells: a potential role for microRNAs -143 and -145

Olivia Crociani (Florence)

HERG1 potassium channels are able to influence VEGF secretion through a macromolecular complex involving the beta1 integrin and the PI3K subunit p85


Coffee break


Giuseppe Fiume (Catanzaro)

Human immunodeficiency virus-1 Tat activates NF-κB through direct interaction with IκB-α and p65

Miriam Gaggianesi (Pavia)

Sam68 defines tumorigenic and metastatic capacity of colon cancer stem cells via CD44v6 and met

Gian Maria Sarra Ferraris (Milan)

Non-integrin cell adhesion triggers ligand-independent integrin signaling

Alessandro Zannini (Trieste)

Pin1 and notch1: a molecular circuitry fueling tumor progression


Stem Cells, Development and Regenerative Medicine

Chairs: Antonio Musarò (Rome)
Giorgio Merlo (Turin)


Luciano Conti (Milan)

The multifaceted essence of CNS stem cells in vitro: developmental properties and physiological relevance


Sara Cioffi (Naples)

Tbx1 is required in endothelial cells to establish vascular patterning in the brain

Alice Conigliaro (Rome)

Stemness in complex epithelial/mesenchymal organ: the liver specific derivatives common origin

Marco Crescenzi (Rome)

Harnessing the cell cycle to the advantage of regenerative medicine


Coffee break


Caterina La Porta (Milan)

CXCR6, a newly defined biomarker of tissue-specific stem cell asymmetric self-renewal, identifies more aggressive human melanoma cancer stem cells?

Giovanni Maroli (Milan)

Pericytes resident in post-natal skeletal muscle differentiate into muscle fibers and enter the satellite cell pool

Giovanni Morrone (Catanzaro)

Inhibition of early B-cell factor 1 activity and modulation of the the B-lymphoid differentiation of primary hematopoietic progenitors by the transcription co-factor zinc finger protein 521 (EHZF/ZNF521)

Daniela Tosoni (Milan)

Numb controls mode of division, proliferative rate and tumorigenic potential of mammary stem cells by regulating the Notch and the p53 pathways


Membrane Trafficking and Organelle Biogenesis

Chairs: Bice Chini (Milan)
Paolo Remondelli (Salerno)


David Stephens (Bristol, UK)

COPII-dependent trafficking - implications for morphogenesis and development


Massimo D'Agostino (Naples)

Molecular mechanism of the dominant form of familial exudative vitreoretinopathy (FEVR)

Nica Borgese (Milan)

Selective activation of ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein

Stefano Vavassori (Milan)

ERp44 acts as a pH-dependent chaperone to retrieve client proteins from the Golgi complex


Coffee break


Antonino Colanzi (Naples)

Mitotic Golgi fragmentation: a G2/M transition checkpoint

Maurizio Renna (Cambridge, UK)

Autophagic substrates clearance requires activity of the syntaxin-5 SNARE complex

Antonella De Jaco (Rome)

Neurolign 3 misfolding mutations and activation of the unfolded protein response

Alessandra Fratangeli (Milan)

Agonists differently regulate endocytic trafficking of the "dual" receptor GPR17 in differentiating oligodendroglial cells


Cell Stress: Survival and Apoptosis

Chairs: Valeria Matranga (Palermo)
Gaetano Cairo (Milan)


Maria Gabriella Santoro (Rome)

The Yin-Yang role of HSF1 in cancer cell survival


Angela Bononi (Ferrara)

PTEN localizes at ER-mitochondria sites and regulates calcium signalling and apoptosis

Andrea Clocchiatti (Udine)

Complex alterations of class IIa HDACs repressive influences observed in breast cancer cell lines: implications for cell survival

Anna Comel (Trieste)

Ser46 phosphorylation and Pin1 mediated isomerization of p53 are key events in p53-dependent apoptosis induced by mutant Huntingtin


Coffee break


Lucia Micale (Foggia)

Understanding the role of TRIM8, a new p53 target gene that modulates p53 activity, in the progression of glioma

Alessandra Montecucco (Pavia)

DNA ligase I deficient cells as model to study the cellular response to chronic replicational stress

Martina Panattoni (Milan)

A role of the COP9 signalosome in modulating DNA-damage responses following DNA replicative stress

Marco Sciacovelli (Padua)

The mitochondrial chaperone TRAP1 regulates tumorigenesis in cancer cell models



ABCD Assembly


Social dinner


Thursday, 8 September

Topic 1: Mechanisms of Signal Transduction
Topic 3: Membrane Trafficking and Organelle Biogenesis

Print poster session A

Topic 1: Mechanisms of Signal Transduction

P1.1 Edoardo Abeni (Brescia)
The study of HCC-cell specific miRs reveals one novel human miR and miR-21, miR-24 and miR-27a differential expression in HCC
P1.2 Ewa Aladowicz (Milan)
RaLP expression favors the invasive potential of melanoma cells
P1.3 Veronica Algisi (Milan)
Heterogeneity in EGFR clathrin endocytosis: vesicles composition impact on receptor signaling and fate
P1.4 Anna Alisi (Rome)
Toll like receptor-4 signaling and downstream transcription factor activated during nonalcoholic fatty liver disease
P1.5 Italia Anna Asteriti (Rome)
The Aurora-A/TPX2 complex: novel regulatory mechanisms and potential role as an oncogenic holoenzyme
P1.6 Monica Bartucci (Rome)
Therapeutic targeting of CHK1 in NSCLC stem cells during chemotherapy
P1.7 Chiara Battistini (Florence)
Involvement of bioactive sphingolipids in skeletal muscle atrophy
P1.9 Jessika Bertacchini (Modena)
Akt phosphorylation at S404 regulates prelamin A through 14.3.3 binding and degradation
P1.10 Massimo Bonora (Ferrara)
Mitochondria dysfunction and differentiation of oligodendrocytes during proinflammatory conditions
P1.11 Giulia Borghetti (Ancona)
The RNA-binding protein Sam68 contributes to ALK-mediated signalling transduction
P1.12 Gianluca Bossi (Rome)
IL-1Ra a putative target gene through which mutant p53-R273H contributes to tumor microenvironment
P1.13 Luca Bravi (Milan)
The absence of CCM3 results in an increase in β-catenin nuclear localization and signaling
P1.14 Sergio Capaccioli (Florence)
Downregulating uPAR expression in human retinal endothelial cells by an antisense oligonucleotide inhibits angiogenesis in a mouse model of proliferative retinopathy
P1.15 Anita Capalbo (Rome)
Signaling pathways that control ER-exit
P1.16 Paola Capitanio (Padua)
The Golgi Apparatus: an heterogeneous intracellular Ca2+ store
P1.17 Rosanna Dattilo (Rome)
Metastatic potential of BCSCs over their differentiated progeny
P1.18 Carmela De Marco (Ariano Irpino)
Cancer-associated E17K mutation of Akt1 is oncogenic in lung epithelial cells through the regulation of Oct-4 transcription factor
P1.19 Diego De Stefani (Padua)
Identification and characterization of the mitochondrial calcium uniporter
P1.20 Serena Duchi (Milan)
The role of V-ATPase in Notch signaling
P1.21 Monica Fabbri (Milan)
Role of Mixed Lineage Kinase 3 (MLK3) in beta-arrestin 2 dependent cell migration
P1.22 Annarita Favia (Rome)
A role for NAADP in Ca2+-dependent pathways activated by VEGF in human endothelial cells
P1.23 Francesca Ferranti (Rome)
Experimental Morphogenetic Field (EMF) promotes cell adhesion, cell spreading and modifies F-actin distribution pattern of TCam-2 seminoma cells
P1.24 Valentina Folgiero (Rome)
Blocking ErbB-3/p85 interaction by a phosphotyrosyl-peptide improves Trastuzumab responsiveness of metastatic ErbB-2 positive breast cancers
P1.25 Angelo Fortunato (Florence)
hERG1 ion channels are involved in cell proliferation and pharmacoresistence in colorectal cancer models.
P1.26 Luca Gasparoli (Florence)
Identification of a MSCs induced potassium elk-like current in a B- chronic leukemia cell line, MEC1
P1.27 Antonella Giammarresi (Milan)
Bimodal pattern of chemokine induced Rap1 activation: dissecting the molecular mechanisms
P1.28 Maria Giubettini (Rome)
Importin beta beyond intracellular transport: a novel regulator of kinetochore function in mitotic cells
P1.29 Irene Granucci (Florence)
Deregulation of the RNA binding protein KSRP-mediated post-transcriptional control is involved in melanoma metastatic phenotype
P1.30 Stefania Graziano (Candiolo (TO))
How to modulate Tie2 activity. From a phage display-based approach to a new interacting protein: Neurexin.
P1.31 Carolina Lage Crespo (Milan)
The PAR/aPKC Complex controls the vectorial migration of medaka macrophages in vivo
P1.32 Cristian Lazzari (Padua)
Effects of Aβ42 oligomers on Ca2+ homeostasis in primary cortical neurons
P1.33 Luigi Maddaluno (Milan)
Modulation of blood brain barrier permeability for a better access of anti-cancer drugs to brain tumors: the CCM/β-catenin crosstalk.
P1.34 Arcangela Gabriella Manente (Novara)
Estrogen Receptor β modulates mitochondrial functions in human  Malignant Pleural Mesothelioma cells
P1.35 Andrea Manfrin (Padua)
A deubiquitinating enzyme for receptor-smads
P1.36 Claudia Mangialardo (Rome)
Thyroid hormone T3 counteracts stz induced diabetes in mouse
P1.37 Simona Martinotti (Alessandria)
Cellular and molecular mechanisms of honey-mediated wound healing
P1.38 Ionica Masgras (Padua)
Analysis of the bioenergetic properties of ρ0 cells
P1.39 Elena Maspero (Milan)
Identifying the signalling mechanism that regulates Nedd4 activity
P1.40 Mara Massimi (L'Aquila)
Phosphodiesterase 4 specific inhibitors control cell growth of human hepatoma HepG2 cells
P1.41 Daniela Mazzà (Rome)
Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal.
P1.42 Elisabetta Meacci (Florence)
Ceramide kinase/C1P axis: a new signalling pathway involved in the antiproliferative action of Vitamin D3 in human neuroblastoma cells
P1.43 Elena Morelli (Milan)
Characterization of the SNARE protein SNAP29 in trafficking, signaling and tumor suppression
P1.44 Marco Napoli (Trieste)
A Pin1/mutant p53 axis promotes aggressiveness in breast cancer
P1.45 Gilda Nappo (Milan)
Quantitative proteomics to identify molecular determinants of EGFR clathrin-independent endocytosis
P1.46 Maria Anna Occhione (Rome)
Characterization of KCASH2 and KCASH3, two novel BTB/POZ proteins involved in cerebellar development and medulloblastoma tumorigenesis
P1.47 Cristina Olgasi (Turin)
Vaccination to kitL: a new approach to inhibit tumor angiogenesis
P1.48 Andrea Orsi (Milan)
Developing sensors for the visualisation of adaptive and ER stress-driven Unfolded Protein Response
P1.49 Aldo Pagano (Genoa)
RNA polymerase III drives alternative splicing of the Potassium Channel Interacting Protein contributing to brain complexity and neurodegeneration
P1.50 Andrea Palamidessi (Milan)
Rab5 couples migratory protrusions and pericellular proteolysis during tumor cell invasion.
P1.51 Serena Pillozzi (Florence)
β1integrin/hERG1 complex as a novel molecular target for antineoplastic therapy
P1.52 Giulia Pinton (Novara)
 PARP1-1 inhibition as a novel therapeutical approach for malignant pleural mesothelioma
P1.53 Mauro Prato (Turin)
Phagocytosis of hemozoin alters MMP-9/TIMP-1 balance in human monocytes: role of cytokines, lipids and NF-κB
P1.54 Valeria Purpura (Rome)
Human keratinocyte early differentiation: involvement of KGFR/FGFR2b expression and signalling.
P1.55 Dunia Ramarli (Verona)
Filamin A-mediated interaction of Prostate Specific Membrane Antigen (PSMA) with beta1 integrin regulates survival of advanced prostate cancer cells.
P1.56 Elia Ranzato (Alessandria)
Epigallocatechin-3-gallate inhibits the growth of malignant mesothelioma cells.
P1.57 Alessandro Rimessi (Ferrara)
Oncogenic RAS-induced neoplastic phenotype is sustained through alterations of calcium homeostasis
P1.58 Erika Rizzo (Padua)
Identification and characterization of a myopathic phenotype affecting skeletal muscles of NG2 null mice
P1.59 Chiara Ronchini (Milan)
The mutations that cooperate with PML/RAR in leukemogenesis form a unique network of functionally homogenous transcriptional deregulations
P1.60 Thomas  Vaccari (Milan)
ESCRT-0 controls Jak/Stat signaling and tumor suppression in Drosophila
P1.61 Eelco van Anken (Milan)
mRNA targeting to endoplasmic reticulum stress signaling sites
P1.62 Andrea Kuan Cie Wong (Padua)
Multiple effects of presenilin-2 mutations linked to familial Alzheimer’s disease on Ca2+ homeostasis: a single organelle FRET-based analysis
P1.63 Andrea Graziani (Novara)
Unacylated ghrelin and ghrelin counteract skeletal muscle atrophy

Topic 3: Membrane Trafficking and Organelle Biogenesis

P3.1 Paola Bagnato (Genoa)
Role of ErbB1 in Trastuzumab-induced ErbB2 signaling and internalization
P3.3 Antonella Bongiovanni (Palermo)
Alix is a substrate of the Ozz-E3 ligase and modulates actin remodeling and plasma membrane stability in skeletal muscle
P3.4 Cecilia Bucci (Lecce)
Vimentin assembly is regulated by the small GTPase Rab7
P3.5 Patrizia Cassella (Milan)
Intracellular trafficking of tail-anchored proteins
P3.6 Bice Chini (Milan)
Oxytocin receceptor trafficking: role of different G-proteins
P3.7 Sara Francesca  Colombo (Milan)
Characterization and identification of new proteins involved into the TRC-40 mediated insertion of tail anchored proteins into the ER membrane
P3.8 Maria De Luca (Lecce)
RILP and V1G1: functional interaction in mammalian cells
P3.9 Matteo Fossati (Milan)
Mechanisms of transmembrane domain-dependent partitioning of membrane proteins whithin the endoplasmic reticulum
P3.11 Carmela Fusco (San Giovanni Rotondo )
TRIM50 forms a complex with HDAC6 and p62/SQSTM1 that localizes to aggresomes
P3.12 Antonino Giovia (Novara)
Imaging calcium-regulated exocytosis in RBL mastocytes with fluorescent polystyrene and mesoporous nanoparticles
P3.13 Rosellina Guarascio (Milan)
Study of the role of EFA6A and EFA6As in the axon initial segment of rat hippocampal neurons
P3.14 Antonella Lupia (Florence)
Both in vitro and in vivo evidences of CD63 tetraspanin impacts on malignant melanoma-associated phenotype: role of TIMP-1, uPAR and MMP
P3.15 Wessen Musa Maruwge (Milan)
Role of EGFR in regulation of solute carriers in cell homeostasis.
P3.16 Maria Elena Miranda Banos (Rome)
Molecular mechanisms of human diseases caused by serpin polymerisation
P3.17 Simona Paladino (Naples)
Plasma membrane organization of GPI-anchored proteins in polarized epithelial cells
P3.18 Rosa Passantino (Palermo)
CLN8 interactors: a possible function of the CLN8 protein in the lipid metabolism and autophagy.
P3.19 Paolo Remondelli (Fisciano-Salerno)
Thapsigargin alters gene expression within the secretory pathway and influences the retention kinetics of the COPII vesicles at the endoplasmic reticulum exit sites 
P3.20 Riccardo Rizzo (Rome)
Mechanism of transport through the Golgi complex
P3.21 Michela Rugolo (Bologna)
Activation of mitochondrial biogenesis as a strategy to improve the energetic function of Leber’s hereditary optic neuropathy cybrids.
P3.22 Margherita Santoriello (Naples)
Rac1 controls cell polarity in FRT thyroid epithelial cells
P3.23 Lenka Stixova (Brno, Czech Republic)
The kinetics and trajectories of chromatin-related proteins
P3.24 Caterina Valetti (Genoa)
Organelle-autonomous regulation of size and number: OA1 receptor sustains Pmel17 expression
P3.25 Sadia Ashraf (Padua)
Tetanus and botulinum toxins need double anchorage to the membrane and intact disulfide bond for low pH induced entry into neurons

Friday, 9 September

Topic 2: Stem Cells, Development and Regenerative Medicine
Topic 4: Cell Stress: Survival and Apoptosis

Print poster session B

Topic 2: Stem Cells, Development and Regenerative Medicine

P2.1 Stefano Bacci (Florence)
Early changes of dendritic cells in human skin wounds
P2.2 Eva Bartova (Brno, Czech Republic)
Chromatin structure and epigenetics of embryonic stem cells
P2.3 Heather M. Bond (Catanzaro)
Zinc finger protein 521 (ZNF521): critical regulatory role in medulloblastoma initiating cells
P2.4 Maria Ida Bonetti (Florence)
Rosiglitazone stimulates dendritic cells generated from human CD133 positive precursors to acquire a highly efficient immunostimulatory phenotype
P2.6 Simona Casarosa (Trento)
Turning stem cells into retina: possible strategies for the cure of retinal degenerations
P2.7 Cristina D'Aniello (Naples)
Unraveling the role of the G-protein coupled receptor APJ in cardiac lineage specification and differentiation
P2.8 Valentina Di Felice (Palermo)
Fibroin and poly-lactic acid scaffolds may be used in cardiac tissue engineering to drive the differentiation of cardiac progenitor cells: in vitro and in vivo studies
P2.9 Chiara Donati (Florence)
S1P induces differentiation of human mesoangioblasts towards smooth muscle cells. A role in vascular regeneration
P2.10 Gemma Flore (Naples)
Tbx1 mutation causes neurodevelopmental abnormalities that may underly sensorimotor gating impairment in a mouse model of 22q11.2 Deletion Syndrome
P2.11 Michela Galdieri (Naples)
Hepatocyte growth factor modulates blood-testis barrier in adult rats
P2.12 Donatella Garzotto (Turin)
The role of ArhGAP15, a negative regulator of the small-GTPase Rac1, in neuronal migration and neuritogenesis during cortical development
P2.13 Mattia Francesco Maria Gerli (Milan)
Exploiting dystrophin gene-dosage compensation by multiple HAC transfer into mesoangioblast stem cells
P2.14 Cristina Giuliani (Bologna)
Changes in DNA methylation patterns of the imprinted locus IGF2/H19 in monozygotic and dyzigotic twin pairs of different ages
P2.15 Paola Grimaldi (Rome)
Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation of neural stem cells
P2.16 Ombretta Guardiola (Naples)
Role of EGF-CFC cripto in skeletal muscle regeneration
P2.17 Gioacchin Iannolo (Viagrande (CT))
Numb expression contributes to the undifferentiated state maintenance in human epithelial stem cells
P2.18 Ilaria Iosue (Rome)
Critical role of c-Myc in Acute Myeloid Leukemia involving direct regulation of miR-26a and histone methyltransferase EZH2
P2.19 Konstantinos Karakostis (Mainz, Germany)
A newly identified Galectin-8 from sea urchin embryos.
P2.20 Dante Lamberti (Rome)
Regulation of GDNF, a paradigm of spermatogonial stem cell niche-derived factor.
P2.21 Sona Legartova (Brno, Czech Republic)
Differentiation of ES cells and deficiency of Suv39h histone methyltransferases is accompanied by distinct levels of A- and B-type lamins
P2.22 Alessandra Longo (Palermo)
PTHrP isoform expression in adipo- and osteo-differentiating human mesenchymal stem cells
P2.23 Giuseppe Lupo (Rome)
Modelling eye specification in embryonic stem cells
P2.24 Pompeo Macioce (Rome)
Hypoxia-regulated expression of β-dystrobrevin and miRNA-143 targeting during Ntera-2 neuronal differentiation
P2.25 Luca Madaro (Rome)
Protein kinase C theta is a key determinant of the inflammatory response involved in the pathogenesis of muscular dystrophy
P2.26 Roberto Madeddu (Sassari)
Prognostic Impact of MGMT Promoter Methylation in 79 Glioblastoma Patients Treated with Temozolamide
P2.27 Marina Mapelli (Milan)
Organizational principles of NuMA/LGN/Gαi complex, and its relation with cellular polarity in asymmetrically dividing stem cells
P2.28 Massimiliano Mazza (Milan)
How AML1-ETO and CDKN1A expression influences the transcriptional program of murine hematopoietic stem cells and early progenitors
P2.29 Giorgio Merlo (Turin)
The role of transcription factors for the development of anterior brain and olfactory connection: a profiling approach.
P2.30 Andrea Messina (Trento)
Activation of the Sonic Hedgehog signaling pathway is necessary for Noggin-mediated retinal induction of Xenopus pluripotent cells
P2.31 Erica Molino (Genoa)
Mesenchymal stem cells induce tumors in an ectopic bone formation model
P2.32 Livia Modica (Milan)
The role of Prep1 in regulating hematopoietic stem cell maintenance
P2.33 Francesco Nicassio (Milan)
Quiescence-keeper microRNAs dampen oncogene-induced transcriptional reprogramming
P2.34 Silvia Nicolis (Milan)
Sox2 molecular functions in neural stem cells maintenance and Shh-dependent brain patterning: insights from conditional mouse mutants
P2.35 Michela Ori (Pisa)
Serotonin 2B receptor signaling is required for craniofacial
and ocular morphogenesis in Xenopus
P2.36 Barbara Ortensi (Milan)
A new regulator of neural progenitor migration and glioblastoma invasion
P2.37 Matteo Ozzano (Novara)
Knock-down of lysosomal cathepsin D negatively impacts on development and life-span of zebrafish
P2.38 Michela Palmisano (Milan)
Modulating the teratogenic potential of the mouse Embryonic Stem Cells (ESCs)
P2.39 Alessio Papi (Bologna)
Nuclear receptor ligands are potent tumor specific anti-inflammatory agents in breast cancer stem cells model
P2.40 Eduardo Jorge Patriarca (Naples)
Metabolic control of pluripotent stem cell metastability
P2.41 Giulia Piaggio (Rome)
Molecular imaging of NF-Y transcriptional activity maps proliferation sites in live animals.
P2.42 Anna Pistocchi (Milan)
From zebrafish (Danio rerio) to mouse, the function of Nfix in skeletal muscle development is partially conserved during the evolution
P2.43 Elisa Resca (Modena)
Human term placenta and stem cells: morphological localization of stem cells “niche” in fetal membranes.
P2.44 Giulia Ricci (Naples)
Spatio-temporal distribution of R-Spondin1 (RSPO1) and its antagonist Dickkopf-1 (DKK1) during prenatal development of the ovary
P2.45 Paolo Romagnoli (Florence)
Rosiglitazone stimulates dendritic cells generated from human CD133 positive precursors to acquire a highly efficient immunostimulatory phenotype
P2.46 Giuliana Rossi (Milan)
The role of Nfix in post-natal myogenesis and muscle regeneration
P2.47 Alessandra Stampella (Rome)
Satisfactory performance of hepatocytes in three-dimensional culture on innovative biopolymeric scaffolds
P2.48 Gabriela Sustackova (Brno, Czech Republic)
Differentiation-independent fluctuation of pluripotency-related transcription factors and other epigenetic marks in embryonic stem cell colonies
P2.49 Ada Maria Tata (Rome)
Cholinergic contribution to Schwann cell differentiation in myelinating phenotype
P2.50 Giuseppina Zapparelli (Rome)
The BH3-mimetic ABT-737 induces death of chemoresistant non small lung cancer stem cells: potential for therapeutics.

Topic 4: Cell Stress: Survival and Apoptosis

P4.1 Roberta Alfieri (Parma)
New therapeutic strategies in the treatment of Non Small Cell Lung Cancer
P4.2 Yolande Asara (Sassari)
Protein expression in MCF7 cells: Cd-5Fu effects
P4.3 M. Inmaculada Ayala Grande (Naples)
Involvement of CtBP1-S/BARS in tumour progression: a specific arget for pharmacological intervention
P4.4 Lucia Babini (Ancona)
Dexamethasone inhibits Fas-induced apoptosis in osteoclasts
P4.5 Rosa Bonaventura (Palermo)
Activation of stress genes in response to UV-B radiation in sea urchin embryos
P4.6 Romina Burla (Rome)
AKTIP, a new lamin interacting protein, is involved in telomere metabolism and DNA replication
P4.7 Artan Ceka (Ancona)
MiRNA characterization in Malignant Mesothelioma tissues and cells
P4.8 Roberto Chiarelli (Palermo)
Relationship between autophagy and apoptosis in Paracentrotus lividus embryos cadmium exposed
P4.9 Laura Cimatti (Trieste)
Long non-coding antisense RNA controls UCHL1 translation through the 5’ overlapping region and an embedded SINEB2 repeat
P4.10 Francesco Ciscato (Padua)
SERPINB3 increases resistance to cisplatin-induced cell death in hepatoma cells through inhibition of the Permeability Transiton Pore
P4.11 Agnese Collino (Milan)
Interplay between genetic and epigenetic modifications in a model of inflammation-driven cancer
P4.12 Laura del Senno (Ferrara)
Quantitative and functional analysis of polycystins in T-lymphoblasts from ADPKD patients and in PKD2-downregulated Jurkat cells
P4.13 Simone Di Franco (Palermo)
P63 role in breast cancer stem cells
P4.14 Michela Faleschini (Trieste)
Identification of microRNAs targeting the DNA damage response in breast cancer
P4.15 Giacoma Galizzi (Palermo)
An early impact of ER stress, inflammation and oxidative stress in the CLN8mnd mouse model of neuronal ceroid lipofuscinosis
P4.16 Fabiana Geraci (Palermo)
Hsp70 is involved in MMP2 level in mouse mesoangioblast stem cells
P4.17 Lina Ghibelli (Rome)
Glycolysis regulates Ca2+ compartmentalization and the onset of stress-induced apoptosis
P4.18 Valentina Giorgio (Padua)
The effects of Idebenone on mitochondrial bioenergetics
P4.19 Giulia Guzzo (Padua)
The mitochondrial chaperone TRAP1 and the regulation of the respiratory chain in tumor cell models
P4.20 Ciro Isidoro (Novara)
Mitochondrial ROS drive autophagy and cell death in dopaminergic neuronal cells: essential role of lysosomal iron
P4.21 Federica Lari (Milan)
Yeast models for unfolded protein response related disorders
P4.22 Rosa Loffredo (Florence)
Preliminary results on functional characterization of Bcl-2-β, a soluble Bcl-2 protein isoform
P4.23 Anna Lukacs (Milan)
CSN5/JAB1 influences oncogene-induced responses in hepatocytes upon MYC induction
P4.24 Matteo Lulli (Florence)
Coenzyme Q10 applied to rat corneas as eye drops, reaches the retina where it protects retinal cells from apoptotic agents: possible application for apoptosis related retinal degenerations
P4.25 Laura Maiorino (Milan)
Role of COP9 signalosome in neoplastic progression in a model of hepatocarcinogenesis
P4.26 Cristina Mammucari (Padua)
Control of mitochondrial Ca2+ uptake by autophagy
P4.27 Saverio Marchi (Ferrara)
The mitochondria-Akt axis as a key determinant in the regulation of autophagy in cancer cells
P4.28 Elettra Sara Marini (Rome)
cFLIP involvement in AKT-mediated sensitivity to ER stress
P4.29 Boris Pantic (Padua)
Myotonic dystrophy protein kinase protects cells from death by favoring hexokinase II association to mitochondria
P4.30 Maria Paola Paronetto (Barcelona, Spain)
The Ewing Sarcoma protein (EWS) regulates DNA damage-induced alternative splicing
P4.31 Simone Patergnani (Ferrara)
The Protein Kinase C β and mitochondria axis as a key regulator of autophagy
P4.32 Andrea Prodosmo (Rome)
p53 centrosomal localization diagnoses ataxia-telangiectasia homozygotes and heterozygotes
P4.33 Maria Antonietta Ragusa (Palermo)
Identification of new members of metallothionein gene family in sea urchin
P4.34 Cinzia Rinaldo (Rome)
HIPK2-mediated phosphorylation of H2B at midbody is critical for cytokinesis
P4.35 Pier Luigi  Rossi (Milan)
A role for LSD1 in acute promyelocytic leukemia
P4.36 Laura Rusconi (Busto Arsizio)
Extrasynaptic NMDA receptor stimulation induces CDKL5 cytoplasmic translocation and proteasomal degradation
P4.37 Gabriele Santini (Ancona)
Circulating microRNAs as new biomarkers in age-related diseases
P4.38 Gabriella Sconzo (Palermo)
Selection of mesoangioblast stem cells more resistant to hydrogen peroxide adverse microenvironments.
P4.39 Paola Sena (Modena)
Quantification and localization of anti-apoptotic matrix metalloproteinase (MMP15 ) in human colorectal carcinogenesis
P4.40 Francesca Siepi (Rome)
Loss of activation loop-Y autophosphorylation of HIPK2 yields to an insoluble misfolded protein
P4.41 Justina Sileikyte (Padua)
Shedding light on the mitochondrial permeability transition
P4.42 Rosalin Dolores Spagnuolo (Milan)
Activation of Hypoxia Inducible Factor(s) as a protective stratagem against various cell injuries
P4.43 Davide Torti (Candiolo (TO))
Cytotoxic versus cytostatic responses in oncogene-addicted cells following oncogene inhibition
P4.44 Andrea Zamperone (Novara)
Anti-apoptotic effects of phenolic extrcts from theombra cacao l., clovamide and epichatechin on rat cardiomyoblasts undergoing oxydative stress

Preparing and setting up your poster

The poster's maximum size is A0 (841 x 1,189 mm; width x height).

Correct format... poster should be PORTRAIT    poster should NOT be LANDSCAPE Wrong format...


The poster sessions are:
Poster Session A, Thu, 18.15-20.30
Poster Session B, Fri, 18:15-20:00


You are expected to have your poster up the latest by lunchtime of the day of your session. Posters should be taken down only the day after your session, during the morning, in time to free your poster slot for the following session. Posters left behind will be removed and discarded by the venue personnel.

Important date

  • Registrations open
    12 April 2011


  • Abstract submissions
    15 July 2011
  • Payment with early bird discount
    20 June 2011
  • Registrations and payment
    31 July 2011
  • Late online registrations
    22 August 2011

Organising Committee

Paolo Pinton (Chair)


Daniela Corda


Giulio Cossu


Giannino Del Sal


Carlotta Giorgi


Bronislava Matoskova


Tullio Pozzan


Roberto Sitia


Silvia Soddu


Guido Tarone